There is a growing concern in the medical field regarding the lack of high-quality, safe, and sustainable bone graft alternatives for critical surgical procedures such as joint replacements, dental implants, and trauma reconstruction. Currently, surgeons often rely on autografts—bone harvested from the patient’s own body—or synthetic substitutes to repair or regenerate damaged bone. While autografts remain the gold standard due to their biological compatibility, they come with significant drawbacks, including limited availability, additional surgical sites, postoperative pain, and increased risk of infection. Synthetic grafts, on the other hand, offer easy availability but often lack the necessary biological properties for proper bone integration and long-term success. This dependency on suboptimal options highlights the urgent need for next-generation bone graft materials that combine strength, biocompatibility, and sustainability. An ideal solution should promote natural bone regeneration while minimizing immune response and surgical complications. Moreover, developing eco-friendly and cost-effective alternatives could make advanced grafting procedures more accessible worldwide.